THE COGNITIVE-BEHAVIORAL ADJUSTMENT AND PERCEPTION OF GENETIC TESTING IN ONCOLOGY PATIENTS WITH A FAMILY HISTORY OF CANCER

Authors

  • Roxana POSTOLICA Doctorand, Universitatea de Medicină şi Farmacie “Grigore T. Popa” Iaşi, Departamentul de Oncogenetică, psiholog clinician Institutul Regional de Oncologie.
  • Magdalena IORGA Şef-lucrări doctor, Universitatea de Medicină şi Farmacie “Grigore T. Popa”, Facultatea de Medicină Generală, Departamentul de Ştiinţe Comportamentale.
  • Doina AZOICA Profesor universitar doctor, Universitatea de Medicină şi Farmacie “Grigore T. Popa” Iaşi, Departamentul de Medicină Preventivă şi Interdisciplinaritate, Coordonator Departamentul de Oncogenetică
  • Cristina Elena STARICA Lector universitar doctor, Universitatea “Petre Andrei” din Iaşi, Departamentul de Ştiinţe Socio-Umane, Facultatea de Psihologie şi Ştiinţele Educaţiei.

Keywords:

cognitive-behavioral adjustment, cancer, genetics, family history.

Abstract

Genetic testing gives rise to fears of a possible illness. A total of 250 subjects were investigated using three measures: Cognitive Emotion Regulation Questionnaire (CERQ), Strategic Approach to Coping Scalescale strategic approach to copingulului (SACS), and the Multidimensional Impact of Cancer Risk Assessment (MICRA). Research objectives were: 1) analysis of perception in terms of emotional stress, uncertainty and benefits of genetic testing of patients with genetic risk of cancer compared with patients without genetic risk and genetic risk healthy individuals in the context of family history of cancer; 2) to analyze the extent to which perception of genetic testing relates to the way in which patitents with genetic risk cope with negative events such as diagnosis, by adopting certain cognitive-behavioral coping and emotional strategies; 3) to analyze how genetic testing depends on the perception of socio-demographic variables (gender, age, education), age at diagnosis, length of time since diagnosis. The analysis of perception regarding genetic tests shows that patients with genetic risk of cancer perceive more benefits and positive experiences of genetic testing compared to other subjects included in the study. Healthy subjects with genetic risk of cancer appreciated in the lowest rate the genetic testing as generating positive experiences and benefits. Addressing the bio-psycho-social oncology genetic aspects could determine a better understanding of how genetic information can contribute to the adoption of healthy behaviors with a positive impact on public health.

References

Budau, O., Ciuca, A., Miclea, M., & Albu, M. (2011). The adaptation and validation process of the Romanian version of the Strategic Approach to Coping Scale (SACS). Cognition, Brain, Behavior. An Interdisciplinary Journal, 15 (1), 131-141.

Cameron, L. D., & Leventhal, H. (2003). Self-regulation, health, and illness: An overview. In L. D. Cameron & H. Leventhal (Eds.), The Self-Regulation of Health and Illness Behaviour (pp. 1-14). New York, NY: Routledge.

Cella, D., Hughes, C., Peterman, A., Chang, C. H., Peshkin, B. N., Schwartz, M. D., Wenzel, L., Lemke, A., Marcus, A. C., & Lerman, C. (2002). A brief assessment of concerns associated with genetic testing for cancer: The Multidimensional Impact of Cancer Risk Assessment (MICRA) Questionnaire. Health Psychology, 2 (16), 564-572.

Claes, E., Denayer, L., Evers-Kiebooms, G., Boogaerts, A., Philippe, K., Tejpar, S., Devriendt, K., & Legius, E. (2005). Predictive testing for hereditary nonpolyposis colorectal cancer: Subjective perception regarding colorectal and endometrial cancer, distress, and health- related behavior at one year post-test. Genetic Testing, 9 (1), 54-65.

Codori, A. M., Petersen, G. M., Miglioretti, D. L., Larkin, E. K., Bushey, M. T., Young, C., Bresinger, J. D., Johnson, K., Bacon, J. A., & Booker, S. V. (1999). Attitudes toward colon cancer gene testing: Factors predicting test uptake. Cancer Epidemiology and Prevention Biomarkers, 8 (1), 345-351.

Durfy, S. J., Bowen, D. J., McTiernan, A., Sporleder, J., & Burke, W. (1999). Attitudes and interest in genetic testing for breast and ovarian cancer susceptibility in diverse groups of women in western Washington. Cancer Epidemiology and Prevention Biomarkers, 8(1), 369-375.

Esplen, M. J., Toner, B., Hunter, J., Glendon, G., Liede, A., Narod, S., Stuckless, N., Butler, K., & Field, B. (2000). A supportive-expressive group intervention for women with a family history of breast cancer: Results of a phase II study. Psycho-Oncology, 9 (3), 243-252.

Evers-Kiebooms, G., Denayer, L., Welikenhuysen, M., Cassiman, J. J., & Berghe, H. (1994). A stigmatizing effect of the carrier status for cystic fibrosis? Clinical Genetics, 46 (5), 336-343.

Fantini-Hauwel, C., Dauvier, B., Arciszewski, T., Antoine, P., & Manouvrier, S. (2011). Genetic testing for hereditary cancer: Effects of alexithymia and coping strategies on variations in anxiety before and after result disclosure. Psychology & Health, 26 (7), 855-873.

Garnefski, N., & Kraaij, V. (2007). The Cognitive Emotion Regulation

Questionnaire: Psychometric features and prospective relationships with depression and anxiety in adults. European Journal of Psychological Assessment, 23 (3), 141-149.

Gopie, J. P., Vasen, H. F., & Tibben, A. (2012). Surveillance for hereditary cancer: Does the benefit outweigh the psychological burden? A systematic review. Critical Reviews in Oncology/Hematology, 83 (3), 329-340.

Hobfoll, S. E., Dunahoo, C. L., Ben-Porath, Y., & Monnier, J. (1994). Gender and coping: The dual-axis model of coping. American Journal of Community Psychology, 22(1), 49-82.

Kaphingst, K. A., Lachance, C. R., & Condit, C. M. (2009). Beliefs about heritability of cancer and health information seeking and preventive behaviors. Journal of Cancer Education, 24 (4), 351-356.

Kash, K. M., & Lerman, C. (1998). Psychological, social, and ethical issues in gene testing. In J. C. Holland (Ed.), Psycho-Oncology (pp. 196-207). New York, NY: Oxford University Press.

Kash, K. M., Holland, J. C., Halper, M. S., & Miller, D. G. (1992). Psychological distress and surveillance behaviors of women with a family history of breast cancer. Journal of the National Cancer Institute, 84 (1), 24-30.

Kim, Y., Valdimarsdottir, H. B., & Bovbjerg, D. H. (2003). Family histories of breast cancer, coping styles, and psychological adjustment. Journal of Behavioral Medicine, 26 (3), 225-243.

Labar, A.-V. (2008). SPSS pentru stiin?ele educa?iei. Iasi: Editura Polirom.

Lerman, C., Lustbader, E., Rimer, B., Daly, M., Miller, S., Sands, C., & Balshem, A. (1995). Effects of individualized breast cancer risk counseling: A randomized trial. Journal of the National Cancer Institute, 87 (4), 286-292.

Leventhal, H., Kim, K., & Leventhal, E. A. (1999). Population risk, actual risk, perceived risk, and cancer control: A discussion. Journal of the National Cancer Institute Monography, 25, 81-85.

Lifford, K. J., Fraser, L., Rosenthal, A. N., Rogers, M. T., Lancastle, D., Phelps, C., Watson, E. K., Clements, A., Iredale, R., Jacobs, I., Menon, U., & Brain, K. E. (2012). Withdrawal from familial ovarian cancer screening for surgery: Findings from a psychological evaluation study (PsyFOCS). Gynecologic Oncology, 124 (1), 158-163.

Lijovic, M., Davis, S. R., Fradkin, P., Bradbury, J., La China, M., Schwarz, M., Wolfe, R., Farrugia, H., & Bell, R. J. (2009). The relationship between knowledge of family history and cancer characteristics at diagnosis in women newly-diagnosed with invasive breast cancer. Familial Cancer, 8 (4), 299-305.

Marteau, T. M., van Duijn, M., & Ellis, I. (1992). Effects of genetic screening on perceptions of health: A pilot study. Journal of Medical Genetics, 29 (1), 24-26.

Perte, A., & Miclea, M. (2011). The standardization of the Cognitive Emotional Regulation Questionnaire (CERQ) on Romanian population. Cognition, Brain, Behavior. An Interdisciplinary Journal, 15 (1), 111-130.

Shiloh, S. (2006). Illness representations, self-regulation, and genetic counseling: A theoretical review. Journal of Genetic Counseling, 15(5), 325-337.

Stiefel, F., Lehmann, A., & Guex, P. (1997). Genetic detection: The need for psychosocial support in modern cancer prevention. Supportive Care in Cancer, 5(6), 461-465.

Tercyak, K. P., Lerman, C., Peshkin, B. N., Hughes, C., Main, D., Isaacs, C., & Schwartz, M. D. (2001). Effects of coping style and BRCA1 and BRCA2 test results on anxiety among women participating in genetic counseling and testing for breast and ovarian cancer risk. Health Psychology, 20 (3), 217-222.

Vernon, S. W., Gritz, E. R., Peterson, S. K., Amos, C. I., Perz, C. A., Baille, W. F., & Lynch, P. M. (1997). Correlates of psychologic distress in colorectal cancer patients undergoing genetic testing for hereditary colon cancer. Health Psychology, 16 (1), 73-86.

Welkenhuysen, M., Evers-Kiebooms, G., Decruyenaere, M., & van den Berghe, H. (1996). Unrealistic optimism and genetic risk. Psychology and Health, 11 (4), 479-492.

Wellisch, D. K., Gritz, E. R., Schain, W., Wang, H. J., & Siau, J. (1991). Psychological functioning of daughters of breast cancer patients. Part I: Daughters and comparison subjects. Psychosomatics, 32(3), 324-336.

Downloads

Published

2016-12-30

How to Cite

POSTOLICA, R., IORGA, M., AZOICA, D., & STARICA, C. E. (2016). THE COGNITIVE-BEHAVIORAL ADJUSTMENT AND PERCEPTION OF GENETIC TESTING IN ONCOLOGY PATIENTS WITH A FAMILY HISTORY OF CANCER. Anuarul Universitatii Petre Andrei Din Iasi - Fascicula: Asistenta Sociala, Sociologie, Psihologie, 17, 35-48. Retrieved from https://www.lumenpublishing.com/journals/index.php/upa-law/article/view/831

Issue

Vol. 17 (2016): Anuarul Universitatii "Petre Andrei" din Iasi - Fascicula: Asistenta Sociala, Sociologie, Psihologie

Section

Articles

License

Authors who publish with this journal agree to the following terms:

  • Authors retain copyright and grant this journal right of first publication, with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work, with an acknowledgement of the work's authorship and initial publication in this journal.
  • Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g. post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  • Authors are permitted and encouraged to post their work online (e.g. in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as an earlier and greater citation of published work (See The Effect of Open Access).