FORENSIC DNA ANALYSIS

Abstract

DNA became a valuable forensic tool in identifying the source of physical evidence left at a crime scene. The use of restriction fragment length polymorphism analysis in the mid-1980s was replaced by polymerase chain reaction methods, which required less high-molecular-weight DNA, were more rapid and more economical. Mitochondrial DNA can be used to provide identifying information when nuclear DNA is insufficient to generate a full genetic profile. Forensic DNA Typing charts the progres and development of DNA applied to criminal forensic, providing certain demonstration of the amazing potential of this method, not only to convict the guilty, but also to exonerate de innocent. DNA analysis has its roots in classical genetics, biochemistry, and molecular biology and it has recently become a major player in criminal investigations and the identification of suspects. This article emphasizes the advantages and limitations of various DNA techniques used in the analysis of forensic evidence. The author presents forensic DNA issues from both a scientific and a legal perspective.